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Strategic financing will advance development of sac-TMT while Merck continues to progress its expansive pipeline.
November 4, 2025
By: Rachel Klemovitch
Assistant Editor
Merck (MSD outside of the United States and Canada) has agreed to receive funds managed by Blackstone Life Sciences (Blackstone) for the development of sacituzumab tirumotecan (sac-TMT). Sac-TMT is an investigational antibody-drug conjugate (ADC) targeting trophoblast cell-surface antigen 2 (TROP2), a protein found on the surface of various cancer cells. Merck is currently evaluating sac-TMT in 15 global Phase 3 clinical trials spanning six tumor types, including breast, endometrial, and lung...
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